Friday 23 November 2018

Why Fossil Fuels?


Do we still want to depend on fossil fuels alone?
Corporate world makes you say YES!!

What a Pathetic situation....
Despite the clean technology of the past decade, we continue to extract and burn fossil fuels more than ever before.
Image result for fossil fuel
For all the millions of words written about climate change, the challenge really comes down to this: fuel is enormously useful, massively valuable and hugely important geopolitically, but tackling global warming means leaving most of it in the ground – by choice. 

Image result for DeforestationWe have colonized this planet enormously and our population density is unimaginable. We have cut down forests, disturbing the habitat of other living beings. Then we started polluting this word by disturbing the Life on this planet. We think this world belong to us, but the fact is we belong to this world.All the life forms have equal rights on the resources, but we loot a lot!!


Fossil Fuels are the only source? Don't we have any alternatives?
Yes !! Definitely we have...
Image result for alternate resources of energyAlternative energy sources can be implemented for houses, cars, factories and any other facility you can imagine. Scientists around the world are researching on developing and discovering new Alternative Energy Sources so that the growing energy needs of human population can be met more easily, safely and efficiently. There are a list of Alternative Energy Sources which will help us maintain the balance of nature without causing it much harm as compared to the conventional energy sources.



Biomass.Jpg
BioMass

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Tidal Power
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Wave Power
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Solar Power
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Geo-Thermal Power
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Wind Power



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CNG
LOT MORE!!!...
 
Not only for the environment sake but also When a nation cant afford fossil fuels, they can invest their money in renewable energy resources and its research.

All the technologies have changes but the energy that we are using is still primitive!!!

Think!

Saturday 5 March 2016

About Zika Virus Disease

Zika virus disease


Zika virus disease (Zika) is a disease caused by Zika virus that is spread to people primarily through the bite of an infected Aedes species mosquito. The most common symptoms of Zika are fever, rash, joint pain, and conjunctivitis (red eyes). The illness is usually mild with symptoms lasting for several days to a week after being bitten by an infected mosquito. People usually don’t get sick enough to go to the hospital, and they very rarely die of Zika. For this reason, many people might not realize they have been infected. Once a person has been infected, he or she is likely to be protected from future infections.Zika EM CDC 280116.tiff
Zika virus was first discovered in 1947 and is named after the Zika forest in Uganda. In 1952, the first human cases of Zika were detected and since then, outbreaks of Zika have been reported in tropical Africa, Southeast Asia, and the Pacific Islands. Zika outbreaks have probably occurred in many locations. Before 2007, at least 14 cases of Zika had been documented, although other cases were likely to have occurred and were not reported. Because the symptoms of Zika are similar to those of many other diseases, many cases may not have been recognized.
In May 2015, the Pan American Health Organization (PAHO) issued an alert regarding the first confirmed Zika virus infection in Brazil and on Feb 1, 2016, the World Health Organization (WHO) declared Zika virus a public health emergency of international concern (PHEIC). Local transmission has been reported in many other countries and territories. Zika virus likely will continue to spread to new areas.

Transmission

Zika virus is transmitted to people primarily through the bite of an infected Aedes species mosquito (A. aegypti and A. albopictus). These are the same mosquitoes that spread dengue and chikungunya viruses.

A mother already infected with Zika virus near the time of delivery can pass on the virus to her newborn around the time of birth.
A pregnant woman can pass Zika virus to her fetus during pregnancy. We are studying the adverse pregnancy and infant outcomes associated with Zika virus infection during pregnancy. To date, there are no reports of infants getting Zika virus through breastfeeding. Because of the benefits of breastfeeding, mothers are encouraged to breastfeed even in areas where Zika virus is found.

Zika virus can be spread by a man to his sex partners. In known cases of likely sexual transmission, the men had Zika symptoms, but the virus can be transmitted before, during, and after symptoms develop. In one case, the virus was spread a few days before symptoms developed.The virus is present in semen longer than in blood.

As of February, 1, 2016, there have not been any confirmed blood transfusion transmission cases in the United States. There have been multiple reports of blood transfusion transmission cases in Brazil. These reports are currently being investigated. During the French Polynesian outbreak, 2.8% of blood donors tested positive for Zika and in previous outbreaks, the virus has been found in blood donors.

Symptoms

  • Most people infected with Zika virus won’t even know they have the disease because they won’t have symptoms. The most common symptoms of Zika are fever, rash, joint pain, or conjunctivitis (red eyes). Other common symptoms include muscle pain and headache. The incubation period (the time from exposure to symptoms) for Zika virus disease is not known, but is likely to be a few days to a week.
    • See your healthcare provider if you are pregnant and develop a fever, rash, joint pain, or red eyes within 2 weeks after traveling to a place where Zika has been reported. Be sure to tell your health care provider where you traveled.
  • The illness is usually mild with symptoms lasting for several days to a week after being bitten by an infected mosquito.
  • People usually don’t get sick enough to go to the hospital, and they very rarely die of Zika. For this reason, many people might not realize they have been infected.
  • Zika virus usually remains in the blood of an infected person for about a week but it can be found longer in some people.
  • Once a person has been infected, he or she is likely to be protected from future infections.

Diagnosis

  • The symptoms of Zika are similar to those of dengue and chikungunya, diseases spread through the same mosquitoes that transmit Zika.
  • See your healthcare provider if you develop the symptoms described above and have visited an area where Zika is found.
  • If you have recently traveled, tell your healthcare provider when and where you traveled.
  • Your healthcare provider may order blood tests to look for Zika or other similar viruses like dengue or chikungunya.

Treatment

  • There is no vaccine to prevent or medicine to treat Zika infections.
  • Treat the symptoms:
    • Get plenty of rest.
    • Drink fluids to prevent dehydration.
    • Take medicine such as acetaminophen (Tylenol®) or paracetamol to relieve fever and pain.
    • Do not take aspirin and other non-steroidal anti-inflammatory drugs.
    • If you are taking medicine for another medical condition, talk to your healthcare provider before taking additional medication.
  • If you have Zika, prevent mosquito bites for the first week of your illness.
    • During the first week of infection, Zika virus can be found in the blood and passed from an infected person to a mosquito through mosquito bites.
    • An infected mosquito can then spread the virus to other people.






Gravitational Waves



What are Gravitational Waves?

Gravitational waves are distortions or 'ripples' in the fabric of space-time caused by some of the most violent and energetic processes in the Universe. Albert Einstein predicted the existence of gravitational waves in 1916 in his general theory of relativity. Einstein's mathematics showed that massive accelerating objects (such as neutron stars or black holes orbiting each other) would disrupt space-time in such a way that 'waves' of distorted space would radiate from the source. Furthermore, these ripples would travel at the speed of light through the Universe, carrying with them information about their cataclysmic origins, as well as invaluable clues to the nature of gravity itself.


The strongest gravitational waves are produced by catastrophic events such as colliding black holes, the collapse of stellar cores (supernovae), coalescing neutron stars or white dwarf stars, the slightly wobbly rotation of neutron stars that are not perfect spheres, and the remnants of gravitational radiation created by the birth of the Universe itself.

Though gravitational waves were predicted to exist in 1916, actual proof of their existence wouldn't arrive until 1974, 20 years after Einstein's death. In that year, two astronomers working at the Arecibo Radio Observatory in Puerto Rico discovered a binary pulsar--two extremely dense and heavy stars in orbit around each other. This was exactly the type of system that, according to general relativity, should radiate gravitational waves. Knowing that this discovery could be used to finally test Einstein's audacious prediction, astronomers began measuring how the period of the stars' orbits changed over time. After eight years of observations, it was determined that the stars were getting closer to each other at precisely the rate predicted by general relativity. This system has now been monitored for over 40 years and the observed changes in the orbit agree so well with general relativity, there is no doubt that it is emitting gravitational waves.



Why Detect Them?




The gravitational waves that are detectible by LIGO will be caused by some of the most energetic events in the Universe—colliding black holes, exploding stars, and even the birth of the Universe itself. Detecting and analyzing the information carried by gravitational waves will allow us to observe the Universe in a way never before possible. This will open up a new window of study on the Universe, giving us a deeper understanding of these cataclysmic events, and usher in brand new cutting-edge studies in physics, astronomy, and astrophysics.
Historically, scientists have relied primarily on observations with electromagnetic radiation (visible light, x-rays, radio waves, microwaves, etc.) to learn about and understand objects and phenomena in the Universe. (In recent years, subatomic particles called neutrinos have also been used to study aspects of the heavens.) Each of these sources of information provides scientists with a different and complementary view of the Universe, with exciting new discoveries occurring as each new 'window' has been discovered, introduced, and utilized.
Gravitational waves are not electromagnetic radiation. They are a completely different phenomena, carrying information about cosmic objects and events that is not carried by electromagnetic radiation. Colliding black holes, for example, emit little or no electromagnetic radiation, but the gravitational waves they emit will cause them to "shine brightly" like beacons on an utterly dark cosmic sea. More importantly, since gravitational waves don't interact with matter (unlike electromagnetic radiation), they travel through the Universe completely unimpeded giving us a crystal clear view of the gravitational-wave Universe. They will carry information about their origins that is free of the distortion or alteration suffered by electromagnetic radiation as it travels through millions of light years of intergalactic space. With this completely new way of examining astrophysical objects and phenomena, gravitational waves will truly open a new window on the Universe, providing astronomers and other scientists with their first glimpses of previously unseen and unseeable wonders, and greatly adding to our understanding of the nature of space and time itself.






Thursday 29 October 2015

First trial to use umbilical cord stem cells to cure HIV

The world’s first clinical trial which aims to cure five HIV patients within three years using transplants of blood from umbilical cords is set to start in Spain.
Image result for umbilical cord stem cells
The project seeks to be the world’s first clinical trial of its kind by recreating the success of Timothy Ray Brown — the only living person ever to be completely cured of HIV, known as “the Berlin patient”.
Plans for the clinical trial were announced last week at a haematology conference in Valencia by Spain’s National Organisation of Transplants (ONT).
ONT has selected 157 donors that have a genetic mutation which allows them to resist HIV, ‘The Local’ reported.
“The Berlin patient”, Brown, was an HIV-positive American living in Berlin in 2006 when he was diagnosed with leukemia.
He needed a transplant to treat the cancer, so his doctor decided to use a donor with a certain cellular mutation that is resistant to HIV.
After Brown received two stem cell transplants from the donor’s bone marrow, his levels of HIV decreased dramatically.
He is now cancer-free and only traces of the virus can found, but they cannot reproduce.
Doctors last year said they successfully performed a similar procedure on a man in Barcelona with lymphoma, but he died of the cancer not long after and they were unable to verify whether the disappearance of the virus was long-term.
To see if Brown’s and the Barcelona patient’s cases can be replicated, the ONT project will look for HIV patients who also have leukemia, lymphoma, or similar illnesses.
The treatment will be more similar to that of the Barcelona patient because doctors will transplant umbilical cord blood into the patients, rather than Brown’s stem cell transplant procedure.
Doctors hope to begin treatments for the first patient between December and January in Madrid.
Source: Hindu News

Friday 12 September 2014

Ebola



Ebola virus disease
Ebola hemorrhagic fever (Ebola HF) is a severe, often-fatal disease in humans and nonhuman primates (monkeys and chimpanzees) that has appeared sporadically since its initial recognition in 1976.
Ebola first appeared in 1976 in 2 simultaneous outbreaks, in Nzara, Sudan, and in Yambuku, Democratic Republic of Congo. The latter was in a village situated near the Ebola River, from which the disease takes its name.
Genus Ebolavirus is 1 of 3 members of the Filoviridae family (filovirus), along with genus Marburgvirus and genus Cuevavirus. 

Marburgvirus and genus Cuevavirus. Genus Ebolavirus comprises 5 distinct species:

  • 1.      Bundibugyo ebolavirus (BDBV)
  • 2.      Zaire ebolavirus (EBOV)
  • 3.      Reston ebolavirus (RESTV)
  • 4.      Sudan ebolavirus (SUDV)
  • 5.      Taï Forest ebolavirus (TAFV).

BDBV, EBOV, and SUDV have been associated with large EVD outbreaks in Africa, whereas RESTV and TAFV have not. The RESTV species, found in Philippines and the People’s Republic of China, can infect humans, but no illness or death in humans from this species has been reported to date.



Transmission

Ebola is introduced into the human population through close contact with the blood, secretions, organs or other bodily fluids of infected animals. In Africa, infection has been documented through the handling of infected chimpanzees, gorillas, fruit bats, monkeys, forest antelope and porcupines found ill or dead or in the rainforest.

Ebola then spreads in the community through human-to-human transmission, with infection resulting from direct contact (through broken skin or mucous membranes) with the blood, secretions, organs or other bodily fluids of infected people, and indirect contact with environments contaminated with such fluids. Burial ceremonies in which mourners have direct contact with the body of the deceased person can also play a role in the transmission of Ebola. Men who have recovered from the disease can still transmit the virus through their semen for up to 7 weeks after recovery from illness.

Health-care workers have frequently been infected while treating patients with suspected or confirmed EVD. This has occurred through close contact with patients when infection control precautions are not strictly practiced.

Among workers in contact with monkeys or pigs infected with Reston ebolavirus, several infections have been documented in people who were clinically asymptomatic. Thus, RESTV appears less capable of causing disease in humans than other Ebola species.

However, the only available evidence available comes from healthy adult males. It would be premature to extrapolate the health effects of the virus to all population groups, such as immuno-compromised persons, persons with underlying medical conditions, pregnant women and children. More studies of RESTV are needed before definitive conclusions can be drawn about the pathogenicity and virulence of this virus in humans.











































Signs and symptoms

EVD is a severe acute viral illness often characterized by the sudden onset of fever, intense weakness, muscle pain, headache and sore throat. This is followed by vomiting, diarrhoea, rash, impaired kidney and liver function, and in some cases, both internal and external bleeding. Laboratory findings include low white blood cell and platelet counts and elevated liver enzymes.
People are infectious as long as their blood and secretions contain the virus. Ebola virus was isolated from semen 61 days after onset of illness in a man who was infected in a laboratory.
The incubation period, that is, the time interval from infection with the virus to onset of symptoms, is 2 to 21 days.



Diagnosis

Other diseases that should be ruled out before a diagnosis of EVD can be made include: malaria, typhoid fever, shigellosis, cholera, leptospirosis, plague, rickettsiosis, relapsing fever, meningitis, hepatitis and other viral haemorrhagic fevers.
Ebola virus infections can be diagnosed definitively in a laboratory through several types of tests:
  •          antibody-capture enzyme-linked immunosorbent assay (ELISA)
  •          antigen detection tests
  •          serum neutralization test
  •          reverse transcriptase polymerase chain reaction (RT-PCR) assay
  •          electron microscopy
  •       virus isolation by cell culture.

Samples from patients are an extreme biohazard risk; testing should be conducted under maximum biological containment conditions.



Vaccine and treatment

No licensed vaccine for EVD is available. Several vaccines are being tested, but none are available for clinical use.
Severely ill patients require intensive supportive care. Patients are frequently dehydrated and require oral rehydration with solutions containing electrolytes or intravenous fluids.
No specific treatment is available. New drug therapies are being evaluated.


Favipiravir looks like it may be useful in a mouse model of the disease. Estrogen receptor drugs used to treat infertility and breast cancer (clomiphene and toremifene) inhibit the progress of Ebola virus in infected mice. Ninety percent of the mice treated with clomiphene and fifty percent of those treated with toremifene survived the tests. Given their oral availability and history of human use, these drugs would be candidates for treating Ebola virus infection in remote geographical locations, either on their own or together with other antiviral drugs.




Prevention and control

Controlling Reston ebolavirus in domestic animals
No animal vaccine against RESTV is available. Routine cleaning and disinfection of pig or monkey farms (with sodium hypochlorite or other detergents) should be effective in inactivating the virus.
If an outbreak is suspected, the premises should be quarantined immediately. Culling of infected animals, with close supervision of burial or incineration of carcasses, may be necessary to reduce the risk of animal-to-human transmission. Restricting or banning the movement of animals from infected farms to other areas can reduce the spread of the disease.
As RESTV outbreaks in pigs and monkeys have preceded human infections, the establishment of an active animal health surveillance system to detect new cases is essential in providing early warning for veterinary and human public health authorities.


Reducing the risk of Ebola infection in people
In the absence of effective treatment and a human vaccine, raising awareness of the risk factors for Ebola infection and the protective measures individuals can take is the only way to reduce human infection and death.

In Africa, during EVD outbreaks, educational public health messages for risk reduction should focus on several factors:
·         Reducing the risk of wildlife-to-human transmission from contact with infected fruit bats or monkeys/apes and the consumption of their raw meat. Animals should be handled with gloves and other appropriate protective clothing. Animal products (blood and meat) should be thoroughly cooked before consumption.

·         Reducing the risk of human-to-human transmission in the community arising from direct or close contact with infected patients, particularly with their bodily fluids. Close physical contact with Ebola patients should be avoided. Gloves and appropriate personal protective equipment should be worn when taking care of ill patients at home. Regular hand washing is required after visiting patients in hospital, as well as after taking care of patients at home.
·         Communities affected by Ebola should inform the population about the nature of the disease and about outbreak containment measures, including burial of the dead. People who have died from Ebola should be promptly and safely buried.

Pig farms in Africa can play a role in the amplification of infection because of the presence of fruit bats on these farms. Appropriate biosecurity measures should be in place to limit transmission. For RESTV, educational public health messages should focus on reducing the risk of pig-to-human transmission as a result of unsafe animal husbandry and slaughtering practices, and unsafe consumption of fresh blood, raw milk or animal tissue. Gloves and other appropriate protective clothing should be worn when handling sick animals or their tissues and when slaughtering animals. In regions where RESTV has been reported in pigs, all animal products (blood, meat and milk) should be thoroughly cooked before eating.



Controlling infection in health-care settings
Human-to-human transmission of the Ebola virus is primarily associated with direct or indirect contact with blood and body fluids. Transmission to health-care workers has been reported when appropriate infection control measures have not been observed.
It is not always possible to identify patients with EBV early because initial symptoms may be non-specific. For this reason, it is important that health-care workers apply standard precautions consistently with all patients – regardless of their diagnosis – in all work practices at all times. These include basic hand hygiene, respiratory hygiene, the use of personal protective equipment (according to the risk of splashes or other contact with infected materials), safe injection practices and safe burial practices.
Health-care workers caring for patients with suspected or confirmed Ebola virus should apply, in addition to standard precautions, other infection control measures to avoid any exposure to the patient’s blood and body fluids and direct unprotected contact with the possibly contaminated environment. When in close contact (within 1 metre) of patients with EBV, health-care workers should wear face protection (a face shield or a medical mask and goggles), a clean, non-sterile long-sleeved gown, and gloves (sterile gloves for some procedures).
Laboratory workers are also at risk. Samples taken from suspected human and animal Ebola cases for diagnosis should be handled by trained staff and processed in suitably equipped laboratories.